This series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers, clinicians and innovators. The series will help attendees anticipate, access, and apply new approaches and technologies for patient care.
The Can-GARD/CCMG Leading Strand Series is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.
To register, click the button below or go to https://us06web.zoom.us/webinar/register/WN_MzE5qgCSQCyPI-X9Ys7_IQ
Mitochondrial Dynamics and Genetic Neuropathy
The presentation will introduce the concept of mitochondrial dynamics and examine how impaired mitochondrial dynamics contributes to genetic neuropathy. Specific emphasis will be placed on CMT2A and pathogenic variants in MFN2, how these variants impact MFN2 functions, and additional pathogenic phenotypes associated with certain MFN2 variants.
Learning Objectives:
- Understand the concept of mitochondrial dynamics and how impairment leads to disease.
- Describe the functions performed by MFN2.
- Recognize that MFN2 variants may impact different MFN2 functions leading to phenotypic variability in CMT2A.
Dr. Timothy Shutt
Dr. Timothy Shutt is an Associate Professor in the Departments of Medical Genetics and Biochemistry & Molecular Biology at the University of Calgary. He obtained his PhD in Biochemistry and Molecular Biology at Dalhousie University, and carried-out post doctoral fellowships at Yale University and the University of Ottawa Heart Institute.
Dr. Shutt’s current research focuses on human mitochondria, essential organelles best known for generating both energy and reactive oxygen species (ROS). However, mitochondria are also key regulators of many other important cellular functions, and their dysfunction is implicated in a broad spectrum of human disorders and aging. Dr. Shutt’s research interests comprise two key aspects of mitochondrial function, mitochondrial dynamics and mitochondrial DNA (mtDNA).
2024-2025 Leading Strand from 12:00pm – 1:00pm ET, scheduled dates are:
Friday September 27, 2024
Friday October 25, 2024
Friday November 22, 2024
Friday December 13, 2024
Friday, January 31, 2025
Friday February 28, 2025
Friday, March 28, 2025
Friday, April 25, 2025
Friday, May 30, 2025
Friday June 27, 2025
Friday, May 16, 2025
Friday, June 20, 2025
