Dr. Lorne Clarke is a professor of medical genetics at the University of British Columbia, Canada and is a clinical and biochemical geneticist in the Provincial Medical Genetics Program for the Province of British Columbia. He received his initial training in biochemistry and medicine at McGill University, and subsequently went on to Dalhousie to complete paediatric residency. He then came West to complete his CCMG clinical and biochemical genetics fellowship with Judith Hall and Derek Applegarth, 1988-1991. His first appointment was a combined one, with our program under Jan Friedman's leadership at the time, and the biochemical disease clinic. He was given lab space and mentorship by Dr Hayden, and launched himself in what would be an outstanding clinician scientist career.

Lorne Clarke headshot

The focus of his three decades as a clinician researcher has been the investigation of the complex series of events at the cellular and tissue level that are at play in the evolution of genetic diseases with the hope that an understanding of disease at this level would result in the development of specific forms of therapy for rare genetic disease. He focused on the basic pathophysiology of lysosomal storage disease and proved that understanding a disease does lead to new therapies.  His group was the first to develop a mouse model of MPS I and recently has produced mouse models of Gaucher disease. His MPS I mouse was instrumental in developing new therapies including at the moment work on fetal therapies.  In addition to basic science, Dr. Clarke’s group has been a key player in numerous clinical trials involving lysosomal storage diseases as well as other rare genetic disorders.

In parallel to his productive research, Dr. Clarke has been a dedicated clinician who has maintained a broad clinical practice throughout his career. He has served two terms as medical director of our Provincial Medical Genetics Program, as well as other leadership roles including acting head of the genetics research cluster at the Child and Family Health Research Institute at UBC. As medical director, he recruited many of our current medical geneticists to BC. He's contributed countless hours of teaching across the department's programs, and is one of the most dedicated Patient Review contributors. We will miss him in so many ways! 

Submitted by Sylvie Langlois and Linlea Armstrong

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2018-02-02 - Dr. Cheryl Rockman-Greenberg Inducted into the Canadian Medical Hall of Fame

The CMHF recognizes and celebrates individuals in medicine whose work has advanced human health and inspires the pursuit of careers in the health sciences. His/her work may be a single meritorious contribution or a lifetime of superior accomplishments. Pioneers in their field, they are role models to young Canadians who wish to pursue careers in health science and a source of inspiration for all Canadians to celebrate the important contributions made by Canadians to global health. Six Canadian medical heroes are inducted annually to the Canadian Medical Hall of Fame. Their work may be a single meritorious contribution or a lifetime of superior accomplishments. Pioneers in their field, they are role models of excellence in health in Canada and the world.

Distinguished Professor of the University of Manitoba, and clinician scientist in the Children’s Hospital Research Institute of Manitoba, Dr. Cheryl Rockman-Greenberg, has devoted her career to bringing advanced medical knowledge and care to isolated and often vulnerable indigenous populations. 


2017-05-08 - Choosing Wisely Canada

Five Things Physicians and Patients Should Question

http://choosingwiselycanada.org/recommendations/medical-genetics/
http://www.choisiravecsoin.org/recommendations/genetique-medicale/

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2015-07-19 - Direct-To-Consumer (DTC) genetic testing in this country

As the voice of Medical Genetics professionals in Canada, CCMG has written a letter, to the Honourable Rona Ambrose, P.C., M.P, Health Canada, to express our concerns with the lack of legislation pertaining to Direct-To-Consumer (DTC) genetic testing in Canada, and the risks this creates for Canadians and the Canadian healthcare system.

Click here to download a copy of the letter.


2015-04-27 - Dr. Judith Hall Inducted into the Canadian Medical Hall of Fame

http://cdnmedhall.org/inductees/dr-judith-g-hall-oc

The CMHF recognizes and celebrates individuals in medicine whose work has advanced human health and inspires the pursuit of careers in the health sciences. His/her work may be a single meritorious contribution or a lifetime of superior accomplishments. Pioneers in their field, they are role models to young Canadians who wish to pursue careers in health science and a source of inspiration for all Canadians to celebrate the important contributions made by Canadians to global health.


2015-02-06 - Dr. Charles Scriver

On the cover: Charles R. Scriver, M.D., President, American Society of Human Genetics, 1986. Since his birth in 1930, Charles R. Scriver has dedicated nearly his entire life in Montreal to making major contributions to the way we understand, detect, and manage inborn errors of metabolism.  Read More...

 


2013-06-14 - CCMG finds Supreme Court Decision on Gene Patents a Step in the Right Direction

CCMG Official Statement on Gene Patents

“In order for Canadians to continue to benefit from the advances of basic and clinical research in health and medicine resulting from the study of the human genome, cost effective health care and optimal interpretation of clinical investigations are needed.  The patenting of DNA and RNA sequences has, and will further, greatly limit the ability of our patients to benefit from progress in the area of human genetics, especially as knowledge continues to rapidly expand with the development of high throughput genomic technologies.  The intention of this document is to highlight the need for a detailed legislative revision of patent laws as they apply to the human genome.” The CCMG Statement on Gene Patents [Clinical Genetics 2012; Volume 82, Issue 5, pages 405–407).


 2013-06-13 - US Supreme Court Decision 

DNA is a product of nature and not patent eligible

No. 12–398. Argued April 15, 2013—Decided June 13, 2013


2012-08-20 - Judgment rendered in patent dispute

Gene patents prevail in a landmark case over two genes associated with hereditary forms of breast and ovarian cancer.


Save the Dates!

TeleGraf and Leading Strand Educational Webinars will return in the fall 2021.

45th Annual Scientific Meeting – May 31 – June 3, 2021Presented Virtually

Annual General Meeting was presented virtually on June 16, 2021 - 01:00 PM ET